Before becoming a filmmaker, Reem worked as a professional scuba diver, and as a human rights officer at the UN and other organizations for over a decade.

Morsi’s many short film include Their Feast (2012 TIFF, BBC, Cine Sud), The Door (Whistler, 2016 & Best Drama (Yorkton 2017 & multiple awards at WIFT Showcase 2018), Show & Tell (2016- WIFT/BravoFact winner) & Multiple Golden Sheaf Awards (Yorkton, 2017). Her multi-genres feature film, Banned, was funded through Telefilm Talent to Watch/CFC/Netflix Accelerator/CCA. Her second feature, “The Last Mark”, screened at TIFF Selects, 2021. Reem has also directed two episodes of “Virgins”, a CBC Gem series and others. Her third feature, “Queen Tut”, starred Alexandra Billings (Transparent) & was released in 2023. She is also in development on her series “Zahra’s Faces” & “Sweet & Sore”.

Morsi’s feature film script, BOOTLEG, received the Rainin scriptwriting grant/the San Francisco Film Society & won the Telefilm Canada New Voices Award, Berlinale Talents Script Station, Torino Comedy Lab, Realness Pan African Screenwriting Residency & La Fabrique des Cinemas du Monde – Festival de Cannes. Morsi is a recipient of The Academy of Canadian Cinema Directors' Program, through which she shadowed on The Handmaid's Tale. She later shadowed on Kim’s Convenience & the Warner Media Director’s Program 2023.